CCL14 Protein (AA 28-93)

N° du produit ABIN6952147

Cette protéine Recombinant CCL14 est exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour CCL14 Protein (AA 28-93) (ABIN6952147)

Antigène: CCL14 (Chemokine (C-C Motif) Ligand 14 (CCL14))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: Escherichia coli (E. coli)

Pureté: > 97 % by SDS PAGE

Détail du produit

Attributs du protein: AA 28-93

Séquence: GPYHPSECCF TYTTYKIPRQ RIMDYYETNS QCSKPGIVFI TKRGHSVCTN PSDKWVQDYI KDMKEN

Attributs du produit: Recombinant Human CCL14 (HCC-1)

niveau d'endotoxine: <0.01 EU per 1μg of the protein by the LAL method

Biological Activity Comment: EC50 = 0.1-0.4 nM determined by Migration Assay in cells expressing recombinant CCR1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water

Stock: -20 °C,-80 °C

Stockage commentaire: 12 months from date of receipt, -20 to -70 °C as supplied.
Suggest to use immediately after reconstitution
1 month at -20 to -70 °C under sterile conditions after reconstitution.

Date de péremption: 12 months

Détail du antigène

Antigène: CCL14 (Chemokine (C-C Motif) Ligand 14 (CCL14))

Autre désignation: CCL14 (HCC-1)

Sujet: Hemofiltrate CC chemokine-1(HCC-1/CCL14) is endogeneously expressed by numerous tissues. Upon processing of the N terminal residues of the full length HCC-1 by the uPA-plasmin system, the active form of HCC-1 (made by ChemoTactics) is a strong agonist for CCR1, CCR5 and to a lesser extent CCR3, and causes chemotaxis of different types of leukocytes. The active form of HCC-1 is also shown as a potent inhibitor of HIV entry.

Poids moléculaire: 7.801 kDa

UniProt: Q16627