SARS-CoV-2 Spike S1 Protein (Fc Tag)

N° du produit ABIN6952624

Cette protéine Recombinant SARS-CoV-2 Spike S1 est exprimée dans HEK-293 Cells et a été mentionnée dans 1 publication.

Aperçu rapide pour SARS-CoV-2 Spike S1 Protein (Fc Tag) (ABIN6952624)

Antigène: SARS-CoV-2 Spike S1

Type de proteíne: Recombinant

Origine: SARS Coronavirus-2 (SARS-CoV-2)

Source: HEK-293 Cells

Application: SDS-PAGE (SDS), ELISA

Pureté: >95 % as determined by SDS-PAGE.

Détail du produit

Purification/Conjugué: Cette SARS-CoV-2 Spike S1 protéine est marqué à la Fc Tag.

Fonction: SARS-CoV-2 (COVID-19) S1 protein, Fc Tag

Séquence: AA 16-685

Attributs du produit: SARS-CoV-2 S1 protein, Fc Tag is expressed from human 293 cells (HEK293). It contains AA Val 16 - Arg 685 (Accession # QHD43416.1). Predicted N-terminus: Val 16
This protein carries a human IgG1 Fc tag at the C-terminus.

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1.0 EU per μg by the LAL method.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Tris, Glycine and NaCl,  pH 7.5

Conseil sur la manipulation: Please avoid repeated freeze-thaw cycles.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: For long term storage, the product should be stored at lyophilized state at -20°C or lower.
This product is stable after storage at:
4-8°C for 12 months in lyophilized state,
-70°C for 3 years under sterile conditions after reconstitution.

Référence

Dogan, Kozhaya, Placek, Gunter, Yigit, Hardy, Plassmeyer, Coatney, Lillard, Bukhari, Kleinberg, Hayes, Arditi, Klapper, Merin, Liang, Gupta, Alpan, Unutmaz: "SARS-CoV-2 specific antibody and neutralization assays reveal the wide range of the humoral immune response to virus." dans: Communications biology, Vol. 4, Issue 1, pp. 129, (2021) (PubMed).

Détail du antigène

Antigène: SARS-CoV-2 Spike S1

Classe de substances: Viral Protein

Sujet: It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Poids moléculaire: 101.5 kDa

ID gène: 43740568

UniProt: P0DTC2