Melanoma gp100 Protein (AA 25-595) (Fc Tag)

N° du produit ABIN6964099

Cette protéine Recombinant Melanoma gp100 est exprimée dans HEK-293 Cells.

Aperçu rapide pour Melanoma gp100 Protein (AA 25-595) (Fc Tag) (ABIN6964099)

Antigène: Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Pureté: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Détail du produit

Attributs du protein: AA 25-595

Purification/Conjugué: Cette Melanoma gp100 protéine est marqué à la Fc Tag.

Fonction: Recombinant human PMEL Protein with C-terminal Human Fc tag

Specificité: PMEL (Lys25-Ala595) hFc (Glu99-Ala330)

Attributs du produit: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))

Autre désignation: PMEL

Sujet: This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2011]

Poids moléculaire: predicted molecular mass of 46.2 kDa after removal of the signal peptide.The apparent molecular mass of PMEL-hFc is 130-250 kDa due to glycosylation.

ID gène: 6490

UniProt: P40967