SARS-CoV-2 Spike Protein (His tag)

N° du produit ABIN7013277

Cette protéine Recombinant SARS-CoV-2 Spike est exprimée dans HEK-293 Cells.

Aperçu rapide pour SARS-CoV-2 Spike Protein (His tag) (ABIN7013277)

Antigène: SARS-CoV-2 Spike

Type de proteíne: Recombinant

Activité biologique: Active

Origine: SARS Coronavirus-2 (SARS-CoV-2)

Source: HEK-293 Cells

Pureté: >95 % as determined by SDS-PAGE.

Détail du produit

Purification/Conjugué: Cette SARS-CoV-2 Spike protéine est marqué à la His tag.

Séquence: AA 16-1213

Specificité: SARS-CoV-2 S protein (F817P, A892P, A899P, A942P, K986P, V987P), His Tag (MALS verified)

Attributs du produit: SARS-CoV-2 S protein, His Tag is expressed from human 293 cells (HEK293). It contains AA Val 16 - Pro 1213 (Accession # QHD43416.1). Proline substitutions (F817P, A892P, A899P, A942P, K986P, V987P) are introduced to stabilize the trimeric prefusion state of SARS-CoV-2 S protein.

niveau d'endotoxine: Less than 1.0 EU per μg by the LAL method.

Information d'application

Indications d'application: MALS verified

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS

Stock: -20 °C

Détail du antigène

Antigène: SARS-CoV-2 Spike

Autre désignation: SARS-CoV-2 S protein

Classe de substances: Viral Protein

Sujet: It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Poids moléculaire: 138.2 kDa