IL-31 Protein (AA 24-164) (His tag)
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- Antigène Voir toutes IL-31 (IL31) Protéines
- IL-31 (IL31) (Interleukin 31 (IL31))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Attributs du protein
- AA 24-164
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette IL-31 protéine est marqué à la His tag.
- Attributs du produit
- Human IL-31 Protein, His Tag (MALS verified)
- Pureté
- >90 % as determined by SDS-PAGE.
- niveau d'endotoxine
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product IL31 Protéine
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Interleukin 31 (IL31) (AA 24-164) protein (His tag)
IL31 Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 31 (IL31) (AA 27-163) protein (His tag)IL31 Origine: Cynomolgus Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 31 (IL31) (AA 24-163) protein (His tag)IL31 Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
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- Indications d'application
- MALS verified
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Stock
- -20 °C
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- Antigène
- IL-31 (IL31) (Interleukin 31 (IL31))
- Autre désignation
- IL-31 (IL31 Produits)
- Synonymes
- IL-31 Protein, 1700013B14Rik Protein, IL31 Protein, interleukin 31 Protein, IL31 Protein, Il31 Protein
- Sujet
- IL-31 is an inflammatory cytokine that helps trigger cell-mediated immunity against pathogens. Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. It has also been identified as a major player in a number of chronic inflammatory diseases, including atopic dermatitis. May function in skin immunity. IL-31 is produced by a variety of cells, namely type 2 helper (TH2) T-cells. IL-31 sends signals through a receptor complex made of IL-31RA and oncostatin M receptor β (OSMRβ) expressed in immune and epithelial cells. These signals activate three pathways: ERK1/2 MAP kinase, PI3K/AKT, and JAK1/2 signaling pathways.
- Poids moléculaire
- 17.7 kDa
- NCBI Accession
- NP_001014358
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