IL-31 Protein (AA 24-164) (His tag)
Aperçu rapide pour IL-31 Protein (AA 24-164) (His tag) (ABIN7013437)
Antigène
Voir toutes IL-31 (IL31) ProtéinesType de proteíne
Activité biologique
Origine
Source
Pureté
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Attributs du protein
- AA 24-164
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Purification/Conjugué
- Cette IL-31 protéine est marqué à la His tag.
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Attributs du produit
- Human IL-31 Protein, His Tag (MALS verified)
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niveau d'endotoxine
- Less than 1.0 EU per μg by the LAL method.
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Interleukin 31 (IL31) (AA 27-163) (Active) protein (His tag)
IL31 Origine: Cynomolgus Hôte: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Interleukin 31 (IL31) (AA 24-163) protein (His tag)IL31 Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Interleukin 31 (IL31) (AA 24-159) protein (His tag)IL31 Origine: Chien Hôte: Baculovirus infected Insect Cells Recombinant > 95 % SDS
Interleukin 31 (IL31) (AA 24-164) protein (Fc Tag)IL31 Origine: Humain Hôte: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Interleukin 31 (IL31) proteinIL31 Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant 97,00% SDS
Interleukin 31 (IL31) proteinIL31 Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant 97,00% SDS
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Indications d'application
- MALS verified
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Stock
- -20 °C
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- IL-31 (IL31) (Interleukin 31 (IL31))
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Autre désignation
- IL-31
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Sujet
- IL-31 is an inflammatory cytokine that helps trigger cell-mediated immunity against pathogens. Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. It has also been identified as a major player in a number of chronic inflammatory diseases, including atopic dermatitis. May function in skin immunity. IL-31 is produced by a variety of cells, namely type 2 helper (TH2) T-cells. IL-31 sends signals through a receptor complex made of IL-31RA and oncostatin M receptor β (OSMRβ) expressed in immune and epithelial cells. These signals activate three pathways: ERK1/2 MAP kinase, PI3K/AKT, and JAK1/2 signaling pathways.
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Poids moléculaire
- 17.7 kDa
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NCBI Accession
- NP_001014358
Antigène
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