CTGF Protein (AA 27-349) (His tag)

N° du produit ABIN7013453

Cette protéine Recombinant CTGF est produite dans HEK-293 Cells.

Aperçu rapide pour CTGF Protein (AA 27-349) (His tag) (ABIN7013453)

Antigène: CTGF (Connective Tissue Growth Factor (CTGF))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Macaque rhésus

Source: HEK-293 Cells

Pureté: >90 % as determined by SDS-PAGE.

Détail du produit

Attributs du protein: AA 27-349

Purification/Conjugué: Cette CTGF protéine est marqué à la His tag.

Attributs du produit: Rhesus macaque CTGF / CCN2 Protein, His Tag

niveau d'endotoxine: Less than 1.0 EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 5 mM HAC,100 mM NaCl, pH 5.5

Stock: -20 °C

Détail du antigène

Antigène: CTGF (Connective Tissue Growth Factor (CTGF))

Autre désignation: CTGF

Sujet: Connective Tissue Growth Factor (CTGF), also known as CCN2, is a member of the CCN (CCN1-6) family of modular matricellular proteins. Like other CCN proteins, mature human CTGF consists of IGF-binding protein domain, a vWF-C domain, a TSP-1 domain, and a cysteine knot heparin-binding domain. CTGF promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. Analysis of CCN2 function in vivo has focused primarily on its key role as a mediator of excess ECM synthesis in multiple fibrotic diseases.

Poids moléculaire: 37.3 kDa

Pathways: Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Growth Factor Binding