K-RAS Protein (AA 2-185) (His tag)

N° du produit ABIN7092804

Protéine Recombinant K-RAS exprimée dans HEK-293 Cells.

Aperçu rapide pour K-RAS Protein (AA 2-185) (His tag) (ABIN7092804)

Antigène: K-RAS (KRAS) (GTPase Kras (KRAS))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Pureté: The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.

Détail du produit

Attributs du protein: AA 2-185

Purification/Conjugué: Cette K-RAS protéine est marqué à la His tag.

Fonction: Recombinant human KRAS protein with C-terminal 6xHis tag

Specificité: KRAS (Thr2-Cys185) 6xHis tag

Attributs du produit: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: K-RAS (KRAS) (GTPase Kras (KRAS))

Autre désignation: KRAS

Classe de substances: Viral Protein

Sujet: This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008]

Poids moléculaire: predicted molecular mass of 21.8 kDa after removal of the signal peptide. The apparent molecular mass of KRAS-His is 15-25 kDa due to glycosylation.

UniProt: P01116