CD5 Protein (CD5) (PE,His tag)
Aperçu rapide pour CD5 Protein (CD5) (PE,His tag) (ABIN7121288)
Antigène
Voir toutes CD5 ProtéinesType de proteíne
Origine
Source
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Purification/Conjugué
- Cette CD5 protéine est marqué à la PE,His tag.
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Fonction
- PE-Labeled Human CD5 Protein, His Tag (Site-specific conjugation)
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Séquence
- Arg 25 - Pro 372
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Attributs du produit
- PE-Labeled Human CD5, His Tag (CD5-HP2H6) is produced via site-specific conjugation of PE to Human CD5, His Tag under optimal conditions with a proprietary technology. Human CD5, His Tag is expressed from human 293 cells (HEK293). It contains AA Arg 25 - Pro 372 (Accession # P06127-1).
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Indications d'application
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 42.2 kDa.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, 0.5 % BSA, pH 7.4
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Stock
- -20 °C
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Stockage commentaire
- -20°C, aviod light
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- CD5
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Autre désignation
- CD5
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Sujet
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Synonyms: CD5,LEU1,
Description: T-cell surface glycoprotein CD5 is also known as Lymphocyte antigen T1/Leu-1 and LEU1,which is phosphorylated on tyrosine residues by LYN,so CD5 can create binding sites for PTPN6/SHP-1.CD5 may act as a receptor in regulating T-cell proliferation. CD5 is expressed at various developmental and activation stages on human B cells.CD5 is a well established negative regulator of TCR and BCR signalling.CD5-positive cells may also prevent the emergence of autoimmunity by provision of cytokines such as IL-10. Development,selection and function of different B- and T-cell subsets or their preferential survival may be directly or indirectly dependent on different glycan structures associated with CD5 or CD5-like molecules. -
Poids moléculaire
- 42.2 kDa
Antigène
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