IL18R1 Protein (Fc-Avi Tag,Biotin)

N° du produit ABIN7199597

Cette protéine Recombinant IL18R1 est exprimée dans HEK-293 Cells.

Aperçu rapide pour IL18R1 Protein (Fc-Avi Tag,Biotin) (ABIN7199597)

Antigène: IL18R1 (Interleukin 18 Receptor 1 (IL18R1))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Pureté: >95 % as determined by SDS-PAGE.

Classe de qualité: MALS verified

Détail du produit

Purification/Conjugué: Cette IL18R1 protéine est marqué à la Fc-Avi Tag,Biotin.

Fonction: Biotinylated Human IL-18 R1 / CD218a Protein, Fc,Avitag™ (SPR & MALS verified)

Séquence: Ala 19 - Arg 329

Attributs du produit: Biotinylated Human IL-18 R1, Fc,Avitag is expressed from human 293 cells (HEK293). It contains AA Ala 19 - Arg 329 (Accession # AAH69575.1).

niveau d'endotoxine: Less than 1.0 EU per μg by the LAL method.

Information d'application

Indications d'application: This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 63.9 kDa. The protein migrates as 70-90 kDa under reducing (R) condition due to glycosylation.

Commentaires:

Ready-to-use Avitag™ biotinylated protein:
The product is exclusively produced using the Avitag™ technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.

This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4

Stock: -20 °C

Stockage commentaire: -20°C

Détail du antigène

Antigène: IL18R1 (Interleukin 18 Receptor 1 (IL18R1))

Autre désignation: IL-18 R1 / CD218a

Sujet: Synonyms: IL18R1,IL1RRP,CD218a,IL18Ra,
Interleukin-18 receptor 1 (IL18R1) is also known as CD218 antigen-like family member A (CD218a), IL1 receptor-related protein (IL-1Rrp or IL1R-rp), CDw218a, IL18Ra, IL1RRP, which belongs to the interleukin-1 receptor family. IL18R1 contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL18R1 is receptor for interleukin 18 (IL-18). IL18R1 binds to the agonist leads to the activation of NF-kappa-B, but does not bind IL1A/interleukin-1 alpha or IL1B/interleukin-1 beta.

Poids moléculaire: 63.9 kDa