HPD Protein (His tag)

N° du produit ABIN7318119

Cette protéine Recombinant HPD est exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour HPD Protein (His tag) (ABIN7318119)

Antigène: HPD (4-Hydroxyphenylpyruvate Dioxygenase (HPD))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Pureté: > 95 % as determined by reducing SDS-PAGE.

Détail du produit

Purification/Conjugué: Cette HPD protéine est marqué à la His tag.

Fonction: Recombinant Human HPD/4HPPD Protein (His Tag)

Séquence: Met 1-Met393

Attributs du produit: Recombinant Human 4-Hydroxyphenylpyruvate Dioxygenase is produced by our E.coli expression system and the target gene encoding Met1-Met393 is expressed with a 6His tag at the N-terminus.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 50 mM NaCl, 1 mM DTT, 20 % Glycerol, pH 8.0.

Agent conservateur: Dithiothreitol (DTT)

Précaution d'utilisation: This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Date de péremption: 6 months

Détail du antigène

Antigène: HPD (4-Hydroxyphenylpyruvate Dioxygenase (HPD))

Autre désignation: HPD/4HPPD

Sujet: 4-Hydroxyphenylpyruvate Dioxygenase,4-Hydroxyphenylpyruvic Acid Oxidase,4HPPD,HPD,HPPDase,PPD,4-Hydroxyphenylpyruvate Dioxygenase (4HPPD) belongs to the 4HPPD family. 4HPPD is a key enzyme in the degradation of tyrosine, which catalyzes the second reaction in the catabolism of tyrosine the conversation of 4-hydroxyphenylpyruvate to homogentisate. 4HPPD exists in homodimer forms, which uses zinc as a cofactor to catalyze the third step in the conversion of L-phenylalanine to fumarate and acetoacetic acid. When the active 4HPPD enzyme concentration is low in the human body, it results in high levels of tyrosine concentration in the blood, which can cause mild mental retardation at birth, and degradation in vision as a patient grows older.

Poids moléculaire:

Calculated MW: 47.1 kDa

Observed MW: 40-50 kDa

ID gène: 3242

UniProt: P32754