ACVA Protein (AA 311-426)

N° du produit ABIN7319736

Cette protéine Recombinant ACVA est produite dans HEK-293 Cells.

Aperçu rapide pour ACVA Protein (AA 311-426) (ABIN7319736)

Antigène: ACVA (Activin A (ACVA))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain, Souris, Rat

Source: HEK-293 Cells

Application: Cell Culture (CC)

Pureté: > 95 % as determined by reducing SDS-PAGE.

Détail du produit

Attributs du protein: AA 311-426

Fonction: Recombinant Human/Mouse/Rat Activin A/INHBA Protein

Séquence: Gly311-Ser426

Attributs du produit: Recombinant Human/Mouse/Rat Activin A is produced by our Mammalian expression system and the target gene encoding Gly311-Ser426 is expressed.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: < 0.01 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Measured by its ability to induce SMAD signaling in 293-Activin A Res cells. The ED₅₀ for this effect is 1.3 ng/ml.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from a 0.2 μm filtered solution of 4 mM HCl.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: ACVA (Activin A (ACVA))

Autre désignation: Activin A/INHBA

Sujet: Activin A,INHBA,Inhibin beta A chain,Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. Activins, members of the TGF-beta superfamily, are disulfide-linked dimeric proteins originally purified from gonadal fluids as proteins that stimulated pituitary follicle stimulating hormone (FSH) release. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Activins are homodimers or heterodimers of the various beta subunit isoforms, while inhibins are heterodimers of a unique alpha subunit and one of the various beta subunits.

Poids moléculaire:

Calculated MW: 13 kDa

Observed MW: 15 kDa

ID gène: 3624

UniProt: P08476

Pathways: Hormone Transport, Peptide Hormone Metabolism