ADIPOQ Protein (His tag)

N° du produit ABIN7320468

Cette protéine Recombinant ADIPOQ est produite dans Escherichia coli (E. coli).

Aperçu rapide pour ADIPOQ Protein (His tag) (ABIN7320468)

Antigène: ADIPOQ (Adiponectin (ADIPOQ))

Type de proteíne: Recombinant

Origine: Souris

Source: Escherichia coli (E. coli)

Pureté: > 95 % as determined by SDS-PAGE

Détail du produit

Purification/Conjugué: Cette ADIPOQ protéine est marqué à la His tag.

Fonction: Recombinant Mouse Adiponectin/AdipoQ Protein (E.coli, His Tag)

Séquence: Glu18-Asn247

Attributs du produit: Recombinant Mouse Adipocyte complement-related 30 kDa protein is produced by our E.coli expression system and the target gene encoding Glu18-Asn247 is expressed with a 6His tag at the N-terminus.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: ADIPOQ (Adiponectin (ADIPOQ))

Autre désignation: Adiponectin/AdipoQ

Sujet:

Background: Adiponectin is a secreted protein. It is synthesized exclusively by adipocytes and secreted into plasma. Adiponectin is an important adipokine that is involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Adiponectin Stimulates AMPK phosphorylation and activates in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Adiponectin also antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. It inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. Adiponectin may play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex: LMW, MMW or HMW.

Synonym: Adiponectin, 30 kDa Adipocyte Complement-Related Protein, Adipocyte complement-related 30 kDa protein, ACRP30, Adipocyte, C1q and Collagen Domain-Containing Protein, Adipose Most Abundant Gene Transcript 1 Protein, apM-1, Gelatin-Binding Protein, ADIPOQ

Poids moléculaire: 27.2 kDa

UniProt: Q60994