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Afamin Protein (AFM) (His tag)

AFM Origine: Humain Hôte: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
N° du produit ABIN7319846
  • Antigène Voir toutes Afamin (AFM) Protéines
    Afamin (AFM)
    Type de proteíne
    Recombinant
    Origine
    • 6
    • 3
    • 3
    Humain
    Source
    • 7
    • 2
    • 1
    • 1
    • 1
    Human Cells
    Purification/Conjugué
    Cette Afamin protéine est marqué à la His tag.
    Fonction
    Recombinant Human Afamin/AFM (C-6His)
    Séquence
    Leu22-Asn599
    Attributs du produit
    Recombinant Human Afamin is produced by our Mammalian expression system and the target gene encoding Leu22-Asn599 is expressed with a 6His tag at the C-terminus.
    Pureté
    >95 % as determined by reducing SDS-PAGE.
    niveau d'endotoxine
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product AFM Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Stock
    4 °C,-20 °C,-80 °C
    Stockage commentaire
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Antigène
    Afamin (AFM)
    Autre désignation
    Afamin/AFM (AFM Produits)
    Synonymes
    AFM Protein, ALB2 Protein, ALBA Protein, ALF Protein, Alf Protein, alpha-Alb Protein, afamin Protein, AFM Protein, Afm Protein
    Sujet

    Background: Afamin also known as Alpha -Albumin is a secreted monomeric glycoprotein of the Alb/Albumin family of molecules. AFM is known to bind and transport vitamin E family molecules, playing an important role for transporting at the blood-brain-barrier. Afamin has been shown to act as extracellular chaperone for poorly soluble, acylated Wnt proteins, forming a stable, soluble complex with functioning Wnt proteins. AFM also serves as an osteoclast-derived chemoattractant for preosteoblasts, providing a rational for the observation that bone formation often follows bone resorption. The importance of Afamin in transport of molecules has led to a suggested diagnostic role in various diseases, including pre-eclampsia, ovarian cancer, and both gestational and type-2 diabetes.

    Synonym: Afamin, AFM, ALB2, ALB2alpha-Alb, ALBA, ALBAalpha-albumin, ALF, Alpha-Alb, Alpha-albumin

    Poids moléculaire
    67.6 kDa
    UniProt
    P43652
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