Fetuin A Protein (His tag)

N° du produit ABIN7320686

Cette protéine Recombinant Fetuin A est produite dans Human Cells.

Aperçu rapide pour Fetuin A Protein (His tag) (ABIN7320686)

Antigène: Fetuin A (AHSG) (alpha-2-HS-Glycoprotein (AHSG))

Type de proteíne: Recombinant

Origine: Souris

Source: Human Cells

Pureté: > 95 % as determined by SDS-PAGE

Détail du produit

Purification/Conjugué: Cette Fetuin A protéine est marqué à la His tag.

Fonction: Recombinant Mouse Fetuin-A/AHSG Protein (His Tag)

Séquence: Ala19-Ile345

Attributs du produit: Recombinant Mouse alpha-2-HS-Glycoprotein is produced by our Mammalian expression system and the target gene encoding Ala19-Ile345 is expressed with a 10His tag at the C-terminus.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, 150 mM NaCl, pH 7.5.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: Fetuin A (AHSG) (alpha-2-HS-Glycoprotein (AHSG))

Autre désignation: Fetuin-A/AHSG

Sujet:

Background: Alpha-2-HS-glycoprotein (AHSG) is a glycoprotein that is composed of two subunits, the A and B chains, belongs to the Cystatin family of proteases inhibitors. It is highly expressed in embryonic cells and adult hepatocytes, and is expressed to a lesser extent in monocytes/macrophages. AHSG is an important circulating inhibitor of calcification in vivo, and is downregulated during the acute-phase response. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. In addition, AHSG may influence the resolution of inflammation by modulating the phagocytosis of apoptotic cells by macrophages. ASHG blocks TGF-beta-dependent signaling in osteoblastic cells.

Synonym: Alpha-2-HS-glycoprotein, Ahsg, Countertrypin, Fetuin-A, Fetua

Poids moléculaire: 36.7 kDa

UniProt: P29699