alpha 2 Antiplasmin Protein (Fc Tag)
Aperçu rapide pour alpha 2 Antiplasmin Protein (Fc Tag) (ABIN7320644)
Antigène
Voir toutes alpha 2 Antiplasmin (SERPINF2) ProtéinesType de proteíne
Origine
Source
Pureté
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Purification/Conjugué
- Cette alpha 2 Antiplasmin protéine est marqué à la Fc Tag.
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Fonction
- Recombinant Mouse SerpinF2/SERPINF2 Protein (Fc Tag)
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Séquence
- Val28-Lys491
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Attributs du produit
- Recombinant Mouse Serine Protease Inhibitor-clade F2 is produced by our Mammalian expression system and the target gene encoding Val28-Lys491 is expressed with a Fc tag at the C-terminus.
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niveau d'endotoxine
- < 1.0 EU per μg as determined by the LAL method.
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Restrictions
- For Research Use only
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Format
- Frozen, Liquid
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Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl,20 % glycerol,1 mM DTT, pH 8.0.
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Stock
- -20 °C
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Stockage commentaire
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- alpha 2 Antiplasmin (SERPINF2) (Alpha2 Antiplasmin (SERPINF2))
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Autre désignation
- SerpinF2/SERPINF2
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Sujet
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Background: Alpha-2-antiplasmin, also called Serpin F2, is a serine protease inhibitor (serpin) responsible for inactivating plasmin, and an important enzyme participates in fibrinolysis and degradation of other proteins. In liver cirrhosis, there is decreased production of alpha 2-antiplasmin, leading to decreased inactivation of plasmin and an increase in fibrinolysis. Serpin F2 is major expressed on liver and kidney. Some other tissues such as muscle, intestine, central nervous system, and placenta also express Serpin F2 mRNA at a moderate level indicated that it is a key regulator of plasmin-mediated proteolysis in these tissues.
Synonym: Alpha-2-antiplasmin, Alpha-2-AP, Alpha-2-plasmin inhibitor, Alpha-2-PI, Serpin F2, Serpinf2
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Poids moléculaire
- 79.3 kDa
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UniProt
- Q61247
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Pathways
- Regulation of Systemic Arterial Blood Pressure by Hormones
Antigène
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