ANGPTL4 Protein (Fc Tag)

N° du produit ABIN7320470

Cette protéine Recombinant ANGPTL4 est produite dans Human Cells.

Aperçu rapide pour ANGPTL4 Protein (Fc Tag) (ABIN7320470)

Antigène: ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))

Type de proteíne: Recombinant

Origine: Souris

Source: Human Cells

Pureté: > 95 % as determined by SDS-PAGE

Détail du produit

Purification/Conjugué: Cette ANGPTL4 protéine est marqué à la Fc Tag.

Fonction: Recombinant Mouse ANGPTL4 Protein (Fc Tag)

Séquence: Lys167-Ser410

Attributs du produit: Recombinant Mouse Angiopoietin Like protein 4 is produced by our Mammalian expression system and the target gene encoding Lys167-Ser410 is expressed with a Fc tag at the C-terminus.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

Stock: -20 °C

Stockage commentaire: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Détail du antigène

Antigène: ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))

Autre désignation: ANGPTL4

Sujet:

Background: Angiopoietin-related protein 4(ANGPTL4)is a secreted protein and contains 1 fibrinogen C-terminal domain. The protein may act as a regulator of angiogenesis and modulate tumorigenesis. It inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 may exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity (By similarity). In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation.

Synonym: Angiopoietin-related protein 4,425O18-1,Angiopoietin-like protein 4,Fasting-induced adipose factor,Hepatic fibrinogen/angiopoietin-related protein,HFARP,Secreted protein Bk89,Angptl4,Farp, Fiaf, Ng27

Poids moléculaire: 54.6 kDa

UniProt: Q9Z1P8

Pathways: Regulation of Lipid Metabolism by PPARalpha