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Biglycan Protein (BGN) (Fc Tag)

Cette protéine Recombinant Biglycan est produite dans HEK-293 Cells.
N° du produit ABIN7320153

Aperçu rapide pour Biglycan Protein (BGN) (Fc Tag) (ABIN7320153)

Antigène

Voir toutes Biglycan (BGN) Protéines
Biglycan (BGN)

Type de proteíne

Recombinant

Origine

  • 9
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Souris

Source

  • 9
  • 7
  • 3
  • 2
  • 1
  • 1
HEK-293 Cells

Pureté

> 85 % as determined by SDS-PAGE
  • Purification/Conjugué

    Cette Biglycan protéine est marqué à la Fc Tag.

    Fonction

    Recombinant Mouse Biglycan/BGN Protein (Fc Tag)

    Séquence

    Met1-Lys369

    Attributs du produit

    A DNA sequence encoding the mouse BGN (Met1-Lys369) was expressed with the Fc region of human IgG1 at the C-terminus.

    niveau d'endotoxine

    < 1.0 EU per μg of the protein as determined by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from sterile PBS, pH 7.4

    Stock

    4 °C,-20 °C,-80 °C

    Stockage commentaire

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Antigène

    Biglycan (BGN)

    Autre désignation

    Biglycan/BGN

    Sujet

    Background: Biglycan, also known as PG-S1 and BGN, is a a small leucine-rich repeat proteoglycan (SLRP). It can be detected in a variety of extracellular matrix tissues, including bone, cartilage and tendon. Biglycan consists of a protein core containing leucine-rich repeat regions and two glycosaminoglycan (GAG) chains consisting of either chondroitin sulfate (CS) or dermatan sulfate (DS). Non-glycanated forms of biglycan (no GAG chains) increase with age in human articular cartilage. Biglycan interacts with collagen, both via the core protein and GAG chains. Biglycan plays a role in the mineralisation of bone. Biglycan core protein binds to the growth factors BMP-4 and influences its bioactivity.

    Synonym: BG,DSPG1,PG-S1,PGI,SLRR1A

    Poids moléculaire

    66.5 kDa

    NCBI Accession

    NP_031568

    Pathways

    Glycosaminoglycan Metabolic Process
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