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Biglycan Protein (BGN) (Fc Tag)

BGN Origine: Souris Hôte: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE
N° du produit ABIN7320153
  • Antigène Voir toutes Biglycan (BGN) Protéines
    Biglycan (BGN)
    Type de proteíne
    Recombinant
    Origine
    • 10
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Souris
    Source
    • 8
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette Biglycan protéine est marqué à la Fc Tag.
    Fonction
    Recombinant Mouse Biglycan/BGN Protein (Fc Tag)
    Séquence
    Met1-Lys369
    Attributs du produit
    A DNA sequence encoding the mouse BGN (Met1-Lys369) was expressed with the Fc region of human IgG1 at the C-terminus.
    Pureté
    > 85 % as determined by SDS-PAGE
    niveau d'endotoxine
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Top Product
    Discover our top product BGN Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, pH 7.4
    Stock
    4 °C,-20 °C,-80 °C
    Stockage commentaire
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Antigène
    Biglycan (BGN)
    Autre désignation
    Biglycan/BGN (BGN Produits)
    Synonymes
    DSPG1 Protein, PG-S1 Protein, PGI Protein, SLRR1A Protein, BG Protein, BSPG1 Protein, bgn Protein, zgc:91989 Protein, dspg1 Protein, pg-s1 Protein, slrr1a Protein, xbgn Protein, BGN Protein, zgc:77123 Protein, DKFZp468I2427 Protein, biglycan Protein, biglycan L homeolog Protein, biglycan a Protein, biglycan S homeolog Protein, biglycan b Protein, BGN Protein, Bgn Protein, bgn.L Protein, bgna Protein, bgn.S Protein, bgn Protein, bgnb Protein
    Sujet

    Background: Biglycan, also known as PG-S1 and BGN, is a a small leucine-rich repeat proteoglycan (SLRP). It can be detected in a variety of extracellular matrix tissues, including bone, cartilage and tendon. Biglycan consists of a protein core containing leucine-rich repeat regions and two glycosaminoglycan (GAG) chains consisting of either chondroitin sulfate (CS) or dermatan sulfate (DS). Non-glycanated forms of biglycan (no GAG chains) increase with age in human articular cartilage. Biglycan interacts with collagen, both via the core protein and GAG chains. Biglycan plays a role in the mineralisation of bone. Biglycan core protein binds to the growth factors BMP-4 and influences its bioactivity.

    Synonym: BG,DSPG1,PG-S1,PGI,SLRR1A

    Poids moléculaire
    66.5 kDa
    NCBI Accession
    NP_031568
    Pathways
    Glycosaminoglycan Metabolic Process
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