CRP Protéine

N° du produit ABIN7194465

Cette protéine Recombinant CRP est produite dans HEK-293 Cells.

Aperçu rapide pour CRP Protéine (ABIN7194465)

Antigène: CRP (C-Reactive Protein (CRP))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Pureté: > 90 % as determined by reducing SDS-PAGE.

Détail du produit

Fonction: Recombinant Human CRP/C-Reactive Protein

Séquence: Met 1-Pro224

Attributs du produit: A DNA sequence encoding the human CRP (P02741-1) (Met1-Pro224) was expressed and purified.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 20 mM Tris, 0.2M NaCl, 5 mM CaCl2, pH 8.0

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: CRP (C-Reactive Protein (CRP))

Autre désignation: CRP/C-Reactive

Sujet:

Background: C-reactive protein (CRP) is synthesized by the liver in response to factors released by fat cells. It is a member of the pentraxin family of proteins. The levels of CRP rise in response to inflammation. Human C-reactive protein (CRP) is the classical acute phase reactant, the circulating concentration of which rises rapidly and extensively in a cytokine-mediated response to tissue injury, infection and inflammation. Serum CRP values are routinely measured, empirically, to detect and monitor many human diseases. However, CRP is likely to have important host defence, scavenging and metabolic functions through its capacity for calcium-dependent binding to exogenous and autologous molecules containing phosphocholine (PC) and then activating the classical complement pathway. CRP may also have pathogenic effects and the recent discovery of a prognostic association between increased CRP production and coronary atherothrombotic events is of particular interest.

Synonym: C-Reactive Protein, CRP, PTX1

Poids moléculaire: 23 kDa

Pathways: Carbohydrate Homeostasis