Cadherin 13 Protein (CDH13) (AA 1-692)
Aperçu rapide pour Cadherin 13 Protein (CDH13) (AA 1-692) (ABIN7321153)
Antigène
Voir toutes Cadherin 13 (CDH13) ProtéinesType de proteíne
Origine
Source
Pureté
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Attributs du protein
- AA 1-692
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Fonction
- Recombinant Rat Cadherin-13/CDH13 Protein
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Séquence
- Met1-Ala692
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Attributs du produit
- A DNA sequence encoding the rat CDH13 (NP_620244.1)(Met1-Ala692) was expressed with six amino acids (LEVLFQ) at the C-terminus.
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Stérilité
- 0.2 μm filtered
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niveau d'endotoxine
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
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Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
Stock
- 4 °C,-20 °C,-80 °C
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Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Date de péremption
- 12 months
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- Cadherin 13 (CDH13)
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Autre désignation
- Cadherin-13/CDH13
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Sujet
- CDH13,CDH13, also known as cadherin-13 and H Cadherin, is a member of the cadherin superfamily. CDH13 acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. CDH13 is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. CDH13 gene is hypermethylated in many types of cancer.
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Poids moléculaire
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Calculated MW: 74.3 kDa
Observed MW: 84-96 kDa
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NCBI Accession
- NP_620244
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UniProt
- A0A096MK38
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Pathways
- EGFR Signaling Pathway, Cell-Cell Junction Organization
Antigène
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