Cathepsin D Protein (CTSD) (His tag)
Aperçu rapide pour Cathepsin D Protein (CTSD) (His tag) (ABIN7320739)
Antigène
Voir toutes Cathepsin D (CTSD) ProtéinesType de proteíne
Origine
Source
Pureté
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Purification/Conjugué
- Cette Cathepsin D protéine est marqué à la His tag.
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Fonction
- Recombinant Mouse Cathepsin D/CTSD Protein (His Tag)
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Séquence
- Ile21-Leu410
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Attributs du produit
- Recombinant Mouse Cathepsin D is produced by our Mammalian expression system and the target gene encoding Ile21-Leu410 is expressed with a 6His tag at the C-terminus.
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niveau d'endotoxine
- < 1.0 EU per μg as determined by the LAL method.
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Cathepsin D (CTSD) (AA 26-412) protein (GST tag)
CTSD Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AA, AP
Cathepsin D (CTSD) (AA 21-410) (Active) protein (His tag)CTSD Origine: Souris Hôte: Baculovirus infected Insect Cells Recombinant > 90% by SDS-PAGE SDS, EAA Active
Cathepsin D (CTSD) (AA 67-403), (partial) protein (GST tag)CTSD Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant 90 % ELISA
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM MES,150 mM NaCl, pH 5.5.
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Stock
- 4 °C,-20 °C,-80 °C
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Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Cathepsin D (CTSD)
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Autre désignation
- Cathepsin D/CTSD
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Sujet
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Background: CTSD localizes to the lysosome and consists of a light chain and a heavy chain. CTSD is expressed in epithelial cells as well as in macrophages.CTSD is a lysosomal aspartyl protease that depends critically on protonation of its active site Asp residue and gets activated at pH 5 in endosome of hepatocytes. It has been suggested to facilitate cancer cell migration and invasion by digesting the basement membrane, extracellular matrix and xonnective tissue. In addition, CTSD has been used as a breast cancer tumor marker.
Synonym: Cathepsin D, CTSD,CPSD
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Poids moléculaire
- 43.9 kDa
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NCBI Accession
- NP_034113
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Pathways
- Peptide Hormone Metabolism
Antigène
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