CD300a Protein (CD300A) (Fc Tag)

N° du produit ABIN7320607

Protéine Recombinant CD300a exprimée dans Human Cells.

Aperçu rapide pour CD300a Protein (CD300A) (Fc Tag) (ABIN7320607)

Antigène: CD300a (CD300A)

Type de proteíne: Recombinant

Origine: Souris

Source: Human Cells

Pureté: > 95 % as determined by SDS-PAGE

Détail du produit

Purification/Conjugué: Cette CD300a protéine est marqué à la Fc Tag.

Fonction: Recombinant Mouse CD300a/LMIR1 Protein (Fc Tag)

Séquence: Leu28-Arg183

Attributs du produit: Recombinant Mouse Leukocyte mono-Ig-like receptor 1 is produced by our Mammalian expression system and the target gene encoding Leu28-Arg183 is expressed with a Fc tag at the C-terminus.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: CD300a (CD300A)

Autre désignation: CD300a/LMIR1

Sujet:

Background: LMIR1, also termed CD300a, is a type I transmembrane glycoprotein with a single IgV-like extracellular domain and an extended membrane proximal region that links the immunoglobulin (Ig) and transmembrane domains and belongs to the immunoglobulin superfamily. The intracellular domain of LMIR1 contains several immunoreceptor tyrosine-based inhibition motifs (ITIMs). When cross-linked, it will be tyrosine phosphorylated and capable of recruiting tyrosine phosphatases (SHP-1, SHP-2) and inositol polyphosphate 5-phosphatase, SHIP. LMIR1 will regulate mast cell-mediated inflammatory responses. LMIR1 is broadly expressed on myeloid and lymphoid cells, and its expression is differentially regulated depending on the cell type.

Synonym: CD300a,CD300a antigen,CMRF35H9, CD300a molecule, leukocyte immunoglobulin-like receptor,CD300 antigen-like family member A, CMRF35-like molecule 8,NK inhibitory receptor, Immunoglobulin superfamily member 12, IRp60,Inhibitory receptor protein 60, CLM8, CMRF-35H, IGSF12, IRC1, IRC2, LMIR1,CLM-8,MAIR-I,Clm8,MAIR-I,MAIR-Ia,mcpir1,MMAC8,Pigr4

Poids moléculaire: 44.3 kDa

UniProt: Q6SJQ0

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process