CD38 Protein (AA 45-304) (Fc Tag)
Aperçu rapide pour CD38 Protein (AA 45-304) (Fc Tag) (ABIN7320857)
Antigène
Voir toutes CD38 ProtéinesType de proteíne
Origine
Source
Pureté
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Attributs du protein
- AA 45-304
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Purification/Conjugué
- Cette CD38 protéine est marqué à la Fc Tag.
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Fonction
- Recombinant Mouse CD38 Protein (Fc Tag)
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Séquence
- Leu45-Thr304
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Attributs du produit
- Recombinant Mouse CD38 is produced by our Mammalian expression system and the target gene encoding Leu45-Thr304 is expressed with a Fc tag at the C-terminus.
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Stérilité
- 0.2 μm filtered
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niveau d'endotoxine
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
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Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, PH7.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
Stock
- 4 °C,-20 °C,-80 °C
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Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Date de péremption
- 12 months
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- CD38
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Sujet
- ADPRC 1-rs1,ADPRC1,CD38,CD38 antigen,CD38 antigen (p45),CD38 Molecule,Cd38,Cd38-rs1,Cyclic ADP-ribose Hydrolase,Cyclic ADP-ribose hydrolase 1,EC 3.2.2.5,I-19,NAD(+) nucleosidase,T10,cADPr hydrolase 1,CD38, also called ADP-ribosyl cyclase, is a Type II integral membrane protein with 301 amino acids in length that belongs to the ADP-ribosyl cyclase family.It synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. And also moonlights as a receptor in cells of the immune system. CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells. Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic beta cells.
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Poids moléculaire
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Calculated MW: 56.9 kDa
Observed MW: 70-90 kDa
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ID gène
- 12494
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UniProt
- P56528
Antigène
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