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CD48 Protein (CD48) (mFc Tag)

CD48 Origine: Humain Hôte: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN7319457
  • Antigène Voir toutes CD48 Protéines
    CD48
    Type de proteíne
    Recombinant
    Origine
    • 14
    • 8
    • 3
    Humain
    Source
    • 14
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human Cells
    Purification/Conjugué
    Cette CD48 protéine est marqué à la mFc Tag.
    Fonction
    Recombinant Human CD48 Protein (mFc Tag)
    Séquence
    Gln27-Ser220
    Attributs du produit
    Recombinant Human SLAM Family Member 2 is produced by our Mammalian expression system and the target gene encoding Gln27-Ser220 is expressed with a mFc tag at the C-terminus.
    Pureté
    > 95 % as determined by reducing SDS-PAGE.
    niveau d'endotoxine
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CD48 Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl, pH 8.0.
    Stock
    4 °C,-20 °C,-80 °C
    Stockage commentaire
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Antigène
    CD48
    Autre désignation
    CD48 (CD48 Produits)
    Synonymes
    AI449234 Protein, AW610730 Protein, BCM1 Protein, BLAST Protein, BLAST-1 Protein, BLAST1 Protein, Bcm-1 Protein, MEM-102 Protein, SLAMF2 Protein, Sgp-60 Protein, hCD48 Protein, mCD48 Protein, CD48 antigen Protein, Cd48 molecule Protein, CD48 molecule Protein, Cd48 Protein, CD48 Protein
    Sujet

    Background: CD48 antigen, also known as B-lymphocyte activation marker BLAST-1, BCM1 surface antigen, Leukocyte antigen MEM-102, TCT.1, CD48, BCM1,and BLAST1, CD48 contains one Ig-like C2-type domain and one Ig-like V-type domain, but does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. CD48 may facilitate interaction between activated lymphocytes and be involved in regulating T-cell activation. CD48 plays a vital role as an environmental sensor for regulating progenitor cell numbers and inhibiting tumor development. It is suggested that the anti-CD48 mAb has the potential to become an effective therapeutic mAb against multiple myeloma.

    Synonym: CD48 antigen, B-lymphocyte activation marker BLAST-1, BCM1 surface antigen, Leukocyte antigen MEM-102, TCT.1, CD48, BCM1,BLAST1,hCD48,mCD48,SLAMF2

    Poids moléculaire
    48.9 kDa
    UniProt
    P09326
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