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CD5L Protein (His tag)

Cette protéine Recombinant CD5L est exprimée dans HEK-293 Cells.
N° du produit ABIN7320432

Aperçu rapide pour CD5L Protein (His tag) (ABIN7320432)

Antigène

Voir toutes CD5L Protéines
CD5L (CD5 Molecule-Like (CD5L))

Type de proteíne

Recombinant

Origine

  • 8
  • 4
  • 2
Souris

Source

  • 6
  • 3
  • 2
  • 1
  • 1
  • 1
HEK-293 Cells

Pureté

> 98 % as determined by SDS-PAGE
  • Purification/Conjugué

    Cette CD5L protéine est marqué à la His tag.

    Fonction

    Recombinant Mouse CD5L Protein (His Tag)

    Séquence

    Met 1-Val 352

    Attributs du produit

    A DNA sequence encoding the extracellular domain (Met 1-Val 352) of mouse CD5L (NP_033820.2) precursor was expressed with a polyhistidine tag at the C-terminus.

    niveau d'endotoxine

    < 1.0 EU per μg of the protein as determined by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from sterile PBS, pH 7.4

    Stock

    4 °C,-20 °C,-80 °C

    Stockage commentaire

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Antigène

    CD5L (CD5 Molecule-Like (CD5L))

    Autre désignation

    CD5L

    Sujet

    Background: CD5L, also known as CD5 antigen-like, is a soluble protein belonging to group B of the scavenger receptor cysteine-rich (SRCR) superfamily and contains three SRCR domains. It is a secreted glycoprotein and expressed by macrophages presentin lymphoid tissues (spleen, lymph node, thymus, and bone marrow). It binds to myelomonocytic and lymphoid cells and may play an important role in the regulation of the innate and adaptive immune systems. CD5L functions as a pattern recognition molecule by binding both lipoteichoic acid (LTA) on Gram positive and lipopolysaccharide (LPS) on Gram negative bacteria. and the SRCR domain 1 of CD5L retains both the LPS and LTA binding activities. In addtion, it is revealed that CD5L seems to play a role as an inhibitor of apoptosis.

    Synonym: CD5 antigen-like,Apoptosis inhibitor expressed by macrophages,Apoptosis inhibitory 6,CT-2,SP-alpha,Cd5l,Aim, Api6,AAC-11, AI047839, Api6, CT2, Pdp, Sp-alpha

    Poids moléculaire

    38 kDa

    NCBI Accession

    NP_033820
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