CD5L Protein (His tag)

N° du produit ABIN7320432

Cette protéine Recombinant CD5L est exprimée dans HEK-293 Cells.

Aperçu rapide pour CD5L Protein (His tag) (ABIN7320432)

Antigène: CD5L (CD5 Molecule-Like (CD5L))

Type de proteíne: Recombinant

Origine: Souris

Source: HEK-293 Cells

Pureté: > 98 % as determined by reducing SDS-PAGE.

Détail du produit

Purification/Conjugué: Cette CD5L protéine est marqué à la His tag.

Fonction: Recombinant Mouse CD5L Protein (His Tag)

Séquence: Met 1-Val 352

Attributs du produit: A DNA sequence encoding the extracellular domain (Met 1-Val 352) of mouse CD5L (NP_033820.2) precursor was expressed with a polyhistidine tag at the C-terminus.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: CD5L (CD5 Molecule-Like (CD5L))

Autre désignation: CD5L

Sujet: AAC-11,AI047839,Aim,Api6,Apoptosis inhibitor expressed by macrophages,Apoptosis inhibitory 6,CD5 antigen-like,CT-2,CT2,Cd5l,Pdp,SP-alpha,Sp-alpha,CD5L, also known as CD5 antigen-like, is a soluble protein belonging to group B of the scavenger receptor cysteine-rich (SRCR) superfamily and contains three SRCR domains. It is a secreted glycoprotein and expressed by macrophages presentin lymphoid tissues (spleen, lymph node, thymus, and bone marrow). It binds to myelomonocytic and lymphoid cells and may play an important role in the regulation of the innate and adaptive immune systems. CD5L functions as a pattern recognition molecule by binding both lipoteichoic acid (LTA) on Gram positive and lipopolysaccharide (LPS) on Gram negative bacteria. and the SRCR domain 1 of CD5L retains both the LPS and LTA binding activities. In addtion, it is revealed that CD5L seems to play a role as an inhibitor of apoptosis.

Poids moléculaire: 38 kDa

NCBI Accession: NP_033820

UniProt: Q9QWK4