CD58 Protein (CD58) (AA 29-215) (His tag)
Aperçu rapide pour CD58 Protein (CD58) (AA 29-215) (His tag) (ABIN7319527)
Antigène
Voir toutes CD58 ProtéinesType de proteíne
Origine
Source
Pureté
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Attributs du protein
- AA 29-215
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Purification/Conjugué
- Cette CD58 protéine est marqué à la His tag.
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Fonction
- Recombinant Human LFA-3/CD58 Protein (His Tag)
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Séquence
- Phe29-Arg215
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Attributs du produit
- Recombinant Human CD58 is produced by our Mammalian expression system and the target gene encoding Phe29-Arg215(His147Tyr) is expressed with a 6His tag at the C-terminus.
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Stérilité
- 0.2 μm filtered
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niveau d'endotoxine
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
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Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
Stock
- 4 °C,-20 °C,-80 °C
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Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Date de péremption
- 12 months
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- CD58
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Autre désignation
- LFA-3/CD58
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Sujet
- Ag3,CD58,CD58 antigen,LFA3,Lymphocyte Function-Associated Antigen 3,Surface Glycoprotein LFA-3,Lymphocyte function-associated antigen 3 (LFA-3/CD58) is a single-pass type I membrane protein. CD58 is widely expressed on hematopoietic and non-hematopoietic human tissue and has been found on leukocytes, erythrocytes, endothelial cells, epithelial cells and fibroblasts of human origin. It is a Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.
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Poids moléculaire
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Calculated MW: 22.5 kDa
Observed MW: 30-60 kDa
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ID gène
- 965
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UniProt
- P19256
Antigène
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