CD59a Protein (CD59A) (His tag)

N° du produit ABIN7320173

Cette protéine Recombinant CD59a est exprimée dans HEK-293 Cells.

Aperçu rapide pour CD59a Protein (CD59A) (His tag) (ABIN7320173)

Antigène: CD59a (CD59A)

Type de proteíne: Recombinant

Origine: Souris

Source: HEK-293 Cells

Pureté: > 92 % as determined by SDS-PAGE

Détail du produit

Purification/Conjugué: Cette CD59a protéine est marqué à la His tag.

Fonction: Recombinant Mouse CD59a/MAC-IP Protein (His Tag)

Séquence: Met 1-Lys 95

Attributs du produit: A DNA sequence encoding the mouse CD59a (O55186) (Met 1-Lys 95), without the pro peptide, was fused with a C-terminal polyhistidine tag.

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: CD59a (CD59A)

Autre désignation: CD59a/MAC-IP

Sujet:

Background: Protectin, a complement regulatory protein, also known as CD59, or MIRL (membrane inhibitor of reactive lysis) is a small protein that inhibits the complement membrane attack complex by binding C5b678 and preventing C9 from binding and polymerizing. The amino-terminal 25 amino acids represented a typical signal peptide sequence and the carboxy-terminal hydrophobic amino acids were characteristic for phosphatidylinositol-anchored proteins.It was found that the CD59/Protectin antigen is a small protein sometimes associated with larger components (45 and 80 kD) in urine. CD59/Protectin antigen was released from the surface of transfected COS cells by phosphatidylinositol-specific phospholipase C, demonstrating that it is attached to the cell membrane by means of a glycolipid anchor, it is therefore likely to be absent from the surface of affected erythrocytes in the disease paroxysmal nocturnal hemoglobinuria.

Synonym: AA987121,Cd59,protectin,RP24-297H17.1

Poids moléculaire: 9.7 kDa

UniProt: O55186