CD6 Protein (CD6) (His tag)

N° du produit ABIN7320847

Protéine Recombinant CD6 exprimée dans Human Cells.

Aperçu rapide pour CD6 Protein (CD6) (His tag) (ABIN7320847)

Antigène: CD6

Type de proteíne: Recombinant

Origine: Souris

Source: Human Cells

Pureté: > 90 % as determined by reducing SDS-PAGE.

Détail du produit

Purification/Conjugué: Cette CD6 protéine est marqué à la His tag.

Fonction: Recombinant Mouse CD6/TP120 Protein (His Tag)

Séquence: Leu18-Gly396

Attributs du produit: Recombinant Mouse CD6 antigen is produced by our Mammalian expression system and the target gene encoding Leu18-Gly396 is expressed with a 6His tag at the C-terminus.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: CD6

Autre désignation: CD6/TP120

Sujet:

Background: CD6 is a member of the group B scavenger receptor cysteinerich(SRCR) superfamily. CD6 is a type I membrane glycoprotein and contains three extracellularSRCR domains. CD6 is expressed at low levels on immature thymocytes and at high levels on mature thymocytes. The majority of peripheral blood T cells, a subsetof B cells, and a subset of neuronal cells express CD6. Mouse CD6 is a 626 amino acid (aa) protein with a 24 aa sequence, a 372 aa extracellular domain, and a204 aa cytoplasmic region. The role of CD6 has not been fully elucidated. However, it appears to play a role as both a costimulatorymolecule in T cell activation and as an adhesion receptor.CD6/ALCAM interactions have been postulated to play a role in thymocyte development. The CD6 intracellular domain contains regions that can interact with SH2 or SH3 containing proteins. However,the signaling pathways have not been elucidated.

Synonym: CD6 antigen, Cd6

Poids moléculaire: 41.9 kDa

UniProt: Q91WN5