Claudin 11 Protein (CLDN11) (Fc Tag)
Aperçu rapide pour Claudin 11 Protein (CLDN11) (Fc Tag) (ABIN7317330)
Antigène
Voir toutes Claudin 11 (CLDN11) ProtéinesType de proteíne
Origine
Source
Pureté
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Purification/Conjugué
- Cette Claudin 11 protéine est marqué à la Fc Tag.
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Fonction
- Recombinant Human CLDN11/Claudin-11 Protein (Fc Tag)
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Séquence
- Val23-Arg82
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Attributs du produit
- A DNA sequence encoding the human CLDN11 (O75508) (Val23-Arg82) was expressed with the Fc region of mouse IgG1 at the N-terminus.
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niveau d'endotoxine
- < 1.0 EU per μg as determined by the LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from sterile PBS, pH 7.4
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Stock
- 4 °C,-20 °C,-80 °C
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Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Claudin 11 (CLDN11)
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Autre désignation
- CLDN11/Claudin-11
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Sujet
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Background: Claudin-11, also known as CLDN11, belongs to the group of claudins. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands function as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions.Claudin-11 is a tight junction associated protein and is a major component of central nervous system (CNS) myelin that is necessary for normal CNS function. Human blood-testis barrier disruption is related to a dysfunction of CLDN11 gene. It plays an important role in regulating proliferation and migration of oligodendrocytes.
Synonym: OSP,OTM
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Poids moléculaire
- 33.2 kDa
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UniProt
- O75508
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Pathways
- Hepatitis C
Antigène
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