LAP3 Protein (His tag)

N° du produit ABIN7317187

Protéine Recombinant LAP3 exprimée dans HEK-293 Cells.

Aperçu rapide pour LAP3 Protein (His tag) (ABIN7317187)

Antigène: LAP3 (Cytosol Aminopeptidase (LAP3))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Pureté: > 90 % as determined by reducing SDS-PAGE.

Détail du produit

Purification/Conjugué: Cette LAP3 protéine est marqué à la His tag.

Fonction: Recombinant Human LAP3/Cytosol Aminopeptidase Protein (His Tag)

Séquence: Met 1-Ala519

Attributs du produit: A DNA sequence encoding the human LAP3 (NP_056991.2) (Met1-Ala519) was expressed with a polyhistidine tag at the C-terminus.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 20 % glycerol, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: LAP3 (Cytosol Aminopeptidase (LAP3))

Autre désignation: LAP3/Cytosol Aminopeptidase

Sujet: HEL-S-106,LAP,LAPEP,PEPS,LAP3 (Leucine Aminopeptidase 3) is a Protein Coding gene. 2 alternative initiation human isoforms have been reported. LAP3, belonging to the peptidase M17 family, has been proved to catalyze the hydrolysis of leucine residues. It catalyzes the removal of unsubstituted N-terminal amino acids from various peptides and is presumably involved in the processing and regular turnover of intracellular proteins. Leucine aminopeptidases are involved in many pathological disorders and regulate cell proliferation, invasion, and/or angiogenesis of tumors. A recent study showed that LAP3 is highly expressed in several malignant and affects tumor angiogenesis. LAP3 is widely expressed in the appendix, lymph node, and other tissues. Diseases associated with LAP3 include Bacterial Vaginosis and Trichomoniasis.

Poids moléculaire: 57.6 kDa

ID gène: 51056

NCBI Accession: NP_056991

UniProt: P28838