beta Defensin 1 Protéine

N° du produit ABIN7319215

Cette protéine Recombinant beta Defensin 1 est produite dans Escherichia coli (E. coli).

Aperçu rapide pour beta Defensin 1 Protéine (ABIN7319215)

Antigène: beta Defensin 1 (DEFB1) (Defensin, beta 1 (DEFB1))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Pureté: > 95 % as determined by reducing SDS-PAGE.

Détail du produit

Fonction: Recombinant Human β-Defensin 1/DEFB1 Protein

Séquence: Gly22-Lys68

Attributs du produit: Recombinant Human beta-Defensin 1 is produced by our E.coli expression system and the target gene encoding Gly22-Lys68 is expressed.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 130 mM NaCl, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: beta Defensin 1 (DEFB1) (Defensin, beta 1 (DEFB1))

Autre désignation: beta-Defensin 1/DEFB1

Sujet:

Background: β-Defensin 1 (DEFB1) is a member of the β-defensin family, which is highly expressed by epithelial cells. β-defensins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal peptide. β-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. β-defensin 1 is an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. Defects in β-Defensin-1 contribute to asthma diagnosis, with apparent gender-specific effects in human. β-defensin 1 may also play a role in the pathogenesis of severe sepsis. In addition, β-defensin 1 is associated with induction profiles in gingival keratinocytes.

Synonym: Beta-Defensin 1, BD-1, hBD-1, Defensin Beta 1, DEFB1, BD1, HBD1

Poids moléculaire: 5.1 kDa

UniProt: P60022