DEFB4A Protéine

N° du produit ABIN7319217

Protéine Recombinant DEFB4A exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour DEFB4A Protéine (ABIN7319217)

Antigène: DEFB4A (DEFB4) (Defensin, beta 4A (DEFB4))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Pureté: > 95 % as determined by reducing SDS-PAGE.

Détail du produit

Fonction: Recombinant Human β-Defensin 4A/DEFB4A Protein

Séquence: Gly24-Pro64

Attributs du produit: Recombinant Human beta-Defensin 4A is produced by our E.coli expression system and the target gene encoding Gly24-Pro64 is expressed.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 130 mM NaCl, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: DEFB4A (DEFB4) (Defensin, beta 4A (DEFB4))

Autre désignation: beta-Defensin 4A/DEFB4A

Sujet:

Background: β-Defensin 4A is a membrane-active cationic peptide that functions in inflammation and innate immune responses. There are at least 30 β-Defensins, which are distinguished from α-Defensins by the connectivity pattern of their three intermolecular disulfide bonds. Members of the Defensin family are highly similar in protein sequence. This gene encodes Defensin, DEFB4, which has broad-spectrum antimicrobial activity and may play an important role in innate epithelial defense. They are highly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. β-Defensin 4A has low expression in salivary gland, bone marrow, colon, stomach, polyp and larynx. No expression in small intestine. The 45 amino acid mature human BD3 shares 38 % and 33 % amino acid sequence identity with mouse and rat BD3, respectively.

Synonym: Beta-Defensin 4A, Beta-Defensin 2, BD-2, hBD-2, Defensin, Beta 2, Skin-Antimicrobial Peptide 1, SAP1, DEFB4A, DEFB102, DEFB2, DEFB4, DEFB4B

Poids moléculaire: 4.3 kDa

UniProt: O15263