ENO1 Protein (His tag)

N° du produit ABIN7319760

Protéine Recombinant ENO1 exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour ENO1 Protein (His tag) (ABIN7319760)

Antigène: ENO1 (Enolase 1 (ENO1))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Pureté: >95 % as determined by reducing SDS-PAGE.

Détail du produit

Purification/Conjugué: Cette ENO1 protéine est marqué à la His tag.

Fonction: Recombinant Human Alpha-enolase/Enolase 1/MPB-1/NNE(C-6His)

Séquence: Met1-Lys434

Attributs du produit: Recombinant Human Alpha-enolase is produced by our E.coli expression system and the target gene encoding Met1-Lys434 is expressed with a 6His tag at the C-terminus.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 250 mM NaCl, 1 mM MgSO4, 20 % Glycerol, pH 7.5 .

Stock: -20 °C

Stockage commentaire: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Détail du antigène

Antigène: ENO1 (Enolase 1 (ENO1))

Autre désignation: Alpha-enolase/Enolase 1/MPB-1/NNE

Sujet: Alpha-enolase, also known as MPB-1, NNE, Enolase 1, belongs to the enolase family. Mammalian enolase is composed of 3 isozyme subunits, alpha, beta and gamma, which can form homodimers or heterodimers which are cell-type and development-specific. ENO1 interacts with PLG in the neuronal plasma membrane and promotes its activation. The C-terminal lysine is required for this binding. Isoform MBP-1 interacts with TRAPPC2B. ENO1 interacts with ENO4 and PGAM2. The alpha/alpha homodimer of ENO1 is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons. During ontogenesis, there is a transition from the alpha/alpha homodimer to the alpha/beta heterodimer in striated muscle cells, and to the alpha/gamma heterodimer in nerve cells. Multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses and may also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. ENO1 also stimulates immunoglobulin production.

Poids moléculaire: 48 kDa

UniProt: P06733