FH Protein (AA 45-510)

N° du produit ABIN7318507

Cette protéine Recombinant FH est exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour FH Protein (AA 45-510) (ABIN7318507)

Antigène: FH (Fumarate Hydratase (FH))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Pureté: > 95 % as determined by reducing SDS-PAGE.

Détail du produit

Attributs du protein: AA 45-510

Fonction: Recombinant Human Fumarase/FH Protein

Séquence: Ala45-Lys510

Attributs du produit: Recombinant Human Fumarase is produced by our E.coli expression system and the target gene encoding Ala45-Lys510 is expressed.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, pH 8.0.

Stock: -20 °C

Stockage commentaire: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Date de péremption: 6 months

Détail du antigène

Antigène: FH (Fumarate Hydratase (FH))

Autre désignation: Fumarase/FH

Sujet: FH,FMRD,Fumarase,Fumarate Hydratase Mitochondrial,HLRCC,LRCC,MCL,MCUL1,Fumarase is an enzyme that catalyze the reversible hydration/dehydration of fumarate to S-malate and is involved in the tricarboxylic acid or Krebs cycle. Fumarase exists in both form, cytosolic formand N-terminal extend mitochondrial form. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension is the same form as in the cytoplasm. Fumarase is thought to act as a tumor suppressor, which deficiency can lead to progressive encephalopathy, cerebral atrophy and development delay.

Poids moléculaire:

Calculated MW: 50.2 kDa

Observed MW: 45 kDa

ID gène: 2271

UniProt: P07954