GABA Protein (GST tag)

N° du produit ABIN7318511

Cette protéine Recombinant GABA est exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour GABA Protein (GST tag) (ABIN7318511)

Antigène: GABA (gamma-Aminobutyric Acid (GABA))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Pureté: > 95 % as determined by reducing SDS-PAGE.

Détail du produit

Purification/Conjugué: Cette GABA protéine est marqué à la GST tag.

Fonction: Recombinant Human GABA Protein (GST Tag)

Séquence: Met 1-Lys117

Attributs du produit: Recombinant Human GABA(A) Receptor-Associated Protein is produced by our E.coli expression system and the target gene encoding Met1-Lys117 is expressed with a GST tag at the N-terminus.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from a 0.2 μm filtered solution of 50 mM Tris-HCl, 200 mM NaCl, pH 7.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: GABA (gamma-Aminobutyric Acid (GABA))

Autre désignation: GABA

Classe de substances: Amino Acid

Sujet: GABA(A) Receptor-Associated Protein,GABARAP,GABARAP Protein,HCG1987397 Isoform CRA_b,Gamma-Aminobutyric Acid Receptor-Associated Protein (GABARAP) is a ligand-gated chloride channel protein that mediates inhibitory neurotransmission and belongs to the MAP1 LC3 family. GABARAP is highly positively charged in its N-terminus and shares sequence similarity with light chain-3 of microtubule-associated proteins 1A and 1B. GABARAP clusters neurotransmitter receptors by mediating interaction with the cytoskeleton. Autophagy is the process by which cells recycle cytoplasm and dispose of excess or defective organelles. This process is suggested to be involved development, differentiation, growth regulation and tissue remodeling in multicellular organisms. An important inhibitory neurotransmitter, GABA, acts on GABA receptors that are ubiquitously expressed in the CNS. GABARAP has been shown to play a important role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton.

Poids moléculaire:

Calculated MW: 40.2 kDa

Observed MW: 37 kDa

UniProt: Q6IAW1