CXCL9 Protein (AA 22-126) (His tag)

N° du produit ABIN7320505

Cette protéine Recombinant CXCL9 est exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour CXCL9 Protein (AA 22-126) (His tag) (ABIN7320505)

Antigène: CXCL9 (gamma-Interferon-Induced Monokine (CXCL9))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Souris

Source: Escherichia coli (E. coli)

Application: Cell Culture (CC)

Pureté: > 98 % as determined by reducing SDS-PAGE.

Détail du produit

Attributs du protein: AA 22-126

Purification/Conjugué: Cette CXCL9 protéine est marqué à la His tag.

Fonction: Recombinant Mouse CXCL9 Protein

Séquence: Thr22-Thr126

Attributs du produit: Recombinant Mouse C-X-C Motif Chemokine 9 is produced by our E.coli expression system and the target gene encoding Thr22-Thr126 is expressed.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: < 0.1 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Measure by its ability to chemoattract BaF3 cells transfected with mouse CXCR3.The ED₅₀ for this effect is <0.3 μg/mL.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: CXCL9 (gamma-Interferon-Induced Monokine (CXCL9))

Autre désignation: CXCL9

Sujet: C-X-C motif chemokine 9,Cxcl9,Gamma-interferon-induced monokine,MIG,Monokine induced by interferon-gamma,Scyb9,Small-inducible cytokine B9,Chemokine (C-X-C motif) ligand 9 (CXCL9, MIG), is a small cytokine belonging to the CXC chemokine family. CXCL9 functions as one of the three ligands of chemokine receptor CXCR3 which is a G protein-coupled receptor found predominantly on T cells. It together with CXCL10 and CXCL11, may activate CXCR3 by binding to it. CXCL9 serves as a cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response. It has been observed that tumour endothelial cells secrete high levels of CXCL9 in all, and CXCL10 in most melanoma metastases. it plays an important role in CD4+ T lymphocyte recruitment and development of CAV, MOMA-2+ macrophages are the predominant recipient-derived source of CXCL9, and recipient CD4 lymphocytes are necessary for sustained CXCL9 production and CAV development in this model.

Poids moléculaire:

Calculated MW: 13.0 kDa

Observed MW: 11-17 kDa

ID gène: 17329

UniProt: P18340