CXCL9 Protéine

N° du produit ABIN7320505

Détail du produit

Antigène: CXCL9 (gamma-Interferon-Induced Monokine (CXCL9))

Type de proteíne: Recombinant

Origine: Souris

Source: Escherichia coli (E. coli)

Fonction: Recombinant Mouse CXCL9 Protein

Séquence: Thr22-Thr126

Attributs du produit: Recombinant Mouse C-X-C Motif Chemokine 9 is produced by our E.coli expression system and the target gene encoding Thr22-Thr126 is expressed.

Pureté: > 95 % as determined by SDS-PAGE

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: CXCL9 (gamma-Interferon-Induced Monokine (CXCL9))

Autre désignation: CXCL9 (CXCL9 Produits)

Synonymes: CMK Protein, Humig Protein, MIG Protein, SCYB9 Protein, crg-10 Protein, BB139920 Protein, Mig Protein, MuMIG Protein, Scyb9 Protein, C-X-C motif chemokine ligand 9 Protein, chemokine (C-X-C motif) ligand 9 Protein, CXCL9 Protein, Cxcl9 Protein

Sujet:

Background: Chemokine (C-X-C motif) ligand 9 (CXCL9, MIG), is a small cytokine belonging to the CXC chemokine family. CXCL9 functions as one of the three ligands of chemokine receptor CXCR3 which is a G protein-coupled receptor found predominantly on T cells. It together with CXCL10 and CXCL11, may activate CXCR3 by binding to it. CXCL9 serves as a cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response. It has been observed that tumour endothelial cells secrete high levels of CXCL9 in all, and CXCL10 in most melanoma metastases. it plays an important role in CD4+ T lymphocyte recruitment and development of CAV, MOMA-2+ macrophages are the predominant recipient-derived source of CXCL9, and recipient CD4 lymphocytes are necessary for sustained CXCL9 production and CAV development in this model.

Synonym: C-X-C motif chemokine 9,Cxcl9,Gamma-interferon-induced monokine,Monokine induced by interferon-gamma,MIG,Small-inducible cytokine B9,Scyb9

Poids moléculaire: 12.3 kDa

UniProt: P18340