GNS Protein (His tag)
Aperçu rapide pour GNS Protein (His tag) (ABIN7318800)
Antigène
Voir toutes GNS ProtéinesType de proteíne
Origine
Source
Pureté
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Purification/Conjugué
- Cette GNS protéine est marqué à la His tag.
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Fonction
- Recombinant Human GNS Protein (His Tag)
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Séquence
- Val37-Leu552
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Attributs du produit
- Recombinant Human N-Acetylglucosamine-6-Sulfatase is produced by our Mammalian expression system and the target gene encoding Val37-Leu552 is expressed with a 6His tag at the C-terminus.
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niveau d'endotoxine
- < 1.0 EU per μg as determined by the LAL method.
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Glucosamine (N-Acetyl)-6-Sulfatase (GNS) (AA 1-552) protein (GST tag)
GNS Origine: Humain Hôte: Wheat germ Recombinant ELISA, WB, AA, AP
Glucosamine (N-Acetyl)-6-Sulfatase (GNS) protein (Myc-DYKDDDDK Tag)GNS Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Restrictions
- For Research Use only
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Format
- Frozen, Liquid
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Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl,10 % Glycerol, pH 8.0.
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Stock
- -20 °C
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Stockage commentaire
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- GNS (Glucosamine (N-Acetyl)-6-Sulfatase (GNS))
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Autre désignation
- GNS
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Sujet
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Background: N-Acetylglucosamine-6-Sulfatase is a member of the Sulfatase family. N-Acetylglucosamine-6-Sulfatase is required for the lysosomal degradation of the Glycosaminoglycans (GAG) Heparan Sulfate and Keratan Sulfate. N-Acetylglucosamine-6-Sulfatase hydrolyzes the 6-Sulfate groups of the N-Acetyl-D-Glucosamine 6-Sulfate units of Heparan Sulfate and Keratan Sulfate. N-Acetylglucosamine-6-Sulfatase binds 1 Calcium ion per subunit. N-Acetylglucosamine-6-Sulfatase deficiency are the cause of Mucopolysaccharidosis Type 3D (MPS3D), an inborn error leading to lysosomal accumulation of heparan sulfate. MPS3D has profound mental deterioration, hyperactivity, and relatively mild somatic manifestations.
Synonym: N-Acetylglucosamine-6-Sulfatase, Glucosamine-6-Sulfatase, G6S, GNS
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Poids moléculaire
- 59.4 kDa
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UniProt
- P15586
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Pathways
- Glycosaminoglycan Metabolic Process
Antigène
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