GSTP1 Protéine

N° du produit ABIN7318541

Détail du produit

Antigène: GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Fonction: Recombinant Human GSTP1 Protein

Séquence: Met 1-Glu210

Attributs du produit: Recombinant Human Glutathione S-Transferase pi 1 is produced by our E.coli expression system and the target gene encoding Met1-Glu210 is expressed.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl,10 % Glycerol, pH 8.0.

Stock: -20 °C

Stockage commentaire: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Détail du antigène

Antigène: GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))

Autre désignation: GSTP1 (GSTP1 Produits)

Synonymes: DFN7 Protein, FAEES3 Protein, GST3 Protein, GSTP Protein, PI Protein, GST-P Protein, Gst3 Protein, Gstp Protein, Gstp2 Protein, gst-Pi Protein, GstpiB Protein, glutathione S-transferase P-like Protein, glutathione S-transferase pi 1 Protein, glutathione S-transferase pi 1 L homeolog Protein, glutathione S-transferase, pi 1 Protein, LOC100739163 Protein, GSTP1 Protein, Gstp1 Protein, LOC100861197 Protein, gstp1.L Protein

Sujet:

Background: Glutathione S-transferase P (GSTP1) is an enzyme that contains 1 GST C-terminal domain, 1 GST N-terminal domain. GSTP1 belongs to the GST superfamily, the GSTs are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. The glutathione S-transferase pi gene (GSTP1) is a polymorphic gene encoding active, functionally different GSTP1 variant proteins. Besides, it regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration. It thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.

Synonym: Glutathione S-transferase P,GSTP1,GST class-pi,GSTP1-1,FAEES3,GST3,

Poids moléculaire: 23.5 kDa

UniProt: P09211

Pathways: Cellular Response to Molecule of Bacterial Origin