HOXA1 Protein (His tag)

N° du produit ABIN7317346

Cette protéine Recombinant HOXA1 est produite dans Escherichia coli (E. coli).

Aperçu rapide pour HOXA1 Protein (His tag) (ABIN7317346)

Antigène: HOXA1 (Homeobox A1 (HOXA1))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Pureté: > 85 % as determined by reducing SDS-PAGE.

Détail du produit

Purification/Conjugué: Cette HOXA1 protéine est marqué à la His tag.

Fonction: Recombinant Human HOXA1 Protein (His Tag)

Séquence: Met 1-His 335

Attributs du produit: A DNA sequence encoding the mature form of human HOXA1 isoform 3 (P49639-1) (Met 1-His 335) was expressed, with a polyhistide tag at the N-terminus.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 50 mM Tris, 30 % glycerol, pH 7.5

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: HOXA1 (Homeobox A1 (HOXA1))

Autre désignation: HOXA1

Sujet:

Background: Homeobox protein Hox-A1 is a transcription factor encoded by HOXA1 gene. This gene is one of the four types of homeobox genes each of which contains a homobox DNA sequence that codes for the homeodomain, a region of 60 amino acids responsible for the DNA binding exhibited by these homeobox proteins. These Homeobox genes are essential metazoan genes as they determine the identity of embryonic regions along the anterio-posterior axis. The homeobox protein Hox-A1 may be involved in the placement of hindbrain segments in the proper location along the anterior-posterior axis during development. Early in its development, the vertebrate hindbrain is transiently subdivided into a series of compartments called rhombomeres. Genes have been identified whose expression patterns distinguish these cellular compartments. Two of these genes, Hoxa1 and Hoxa2, have been shown to be required for proper patterning of the early mouse hindbrain and the associated neural crest. It has been detected HOXA1 expression in a variety of human breast cancer lesions, suggesting that HOXA1 may be required for the establishment of breast cancer cells phenotype. 

Synonym: BSAS;HOX1;HOX1F

Poids moléculaire: 38 kDa

Pathways: Sensory Perception of Sound