HOXB4 Protein (His tag)
Aperçu rapide pour HOXB4 Protein (His tag) (ABIN7319405)
Antigène
Voir toutes HOXB4 ProtéinesType de proteíne
Origine
Source
Pureté
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Purification/Conjugué
- Cette HOXB4 protéine est marqué à la His tag.
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Fonction
- Recombinant Human HOXB4 Protein (His Tag)
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Séquence
- Met1-Leu251
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Attributs du produit
- Recombinant Human Homeobox protein B4 is produced by our E.coli expression system and the target gene encoding Met1-Leu251 is expressed with a 6His tag at the N-terminus.
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niveau d'endotoxine
- < 1.0 EU per μg as determined by the LAL method.
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Homeobox B4 (HOXB4) (AA 1-250) protein (His tag)
custom-made HOXB4 Origine: Souris Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Homeobox B4 (HOXB4) (AA 1-251) protein (His tag)custom-made HOXB4 Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Homeobox B4 (HOXB4) (AA 1-60) protein (GST tag)HOXB4 Origine: Humain Hôte: Wheat germ Recombinant ELISA, WB, AP, AA
Homeobox B4 (HOXB4) (AA 1-251), (full length) protein (His tag)HOXB4 Origine: Humain Hôte: Levure Recombinant > 90 % SDS
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Restrictions
- For Research Use only
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Format
- Frozen, Liquid
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Buffer
- Supplied as a 0.2 μm filtered solution of 4 mM HCl.
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Stock
- -20 °C
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Stockage commentaire
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- HOXB4 (Homeobox B4 (HOXB4))
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Autre désignation
- HOXB4
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Sujet
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Background: Homeobox B4 (HOXB4) is encoded by the HOXB4 gene which is a member of the the class I homeobox (HOX) gene family and encodes a nuclear protein with a homeobox DNA-binding domain. These genes are master control regulators of developmental programs including embryonic and adult hematopoiesis. Multiple HOX genes, including HOXB4, are highly expressed in the hematopoietic stem cells (HSC) compartment. HOXB4 gene can act in opposite ways when expressed by different cells, promoting the proliferation of stem cells whilst activating the apoptotic pathway in some embryonic structures. The protein HOXB4, as a homeodomain transcription factor, has been shown to be an important regulator of stem cell renewal and hematopoiesis. Incellular or ectopic expression of HOXB4 expands hematopoietic stem and progenitor cells in vivo and in vitro, making it a potential candidate for therapeutic stem cell expansion.
Synonym: Homeobox protein Hox-B4, Homeobox protein Hox-2.6, Homeobox protein Hox-2F, HOXB4, HOX2F
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Poids moléculaire
- 29.8 kDa
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UniProt
- P17483
Antigène
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