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HYAL1 Protein (His tag)

HYAL1 Origine: Humain Hôte: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN7318588
  • Antigène Voir toutes HYAL1 Protéines
    HYAL1 (Hyaluronidase-1 (HYAL1))
    Type de proteíne
    Recombinant
    Origine
    • 9
    • 3
    • 1
    • 1
    • 1
    Humain
    Source
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Human Cells
    Purification/Conjugué
    Cette HYAL1 protéine est marqué à la His tag.
    Fonction
    Recombinant Human Hyaluronidase-1/HYAL1 Protein (His Tag)
    Séquence
    Phe22-Trp435
    Attributs du produit
    Recombinant Human Hyaluronidase-1 is produced by our Mammalian expression system and the target gene encoding Phe22-Trp435 is expressed with a 6His tag at the C-terminus.
    Pureté
    > 95 % as determined by reducing SDS-PAGE.
    niveau d'endotoxine
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product HYAL1 Protéine
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, 10 % Glycerol, pH 7.5.
    Stock
    -20 °C
    Stockage commentaire
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Antigène
    HYAL1 (Hyaluronidase-1 (HYAL1))
    Autre désignation
    Hyaluronidase-1/HYAL1 (HYAL1 Produits)
    Synonymes
    HYAL-1 Protein, LUCA1 Protein, NAT6 Protein, Hya1 Protein, Hyal-1 Protein, hyaluronoglucosaminidase 1 Protein, HYAL1 Protein, Hyal1 Protein
    Sujet

    Background: Hyaluronidase-1 (HYAL1) is a secreted lysosomal hyaluronidase that belongs to the glycosyl hydrolase 56 family. HYAL1 contains one EGF-like domain and is highly expressed in the liver, kidney, and heart, but it is weakly expressed in the lung, placenta, and skeletal muscle. HYAL1 is thought to be involved in cell proliferation, migration, and differentiation. It may play a role in promoting tumor progression and blocking the TGFB1-enhanced cell growth. Mutations in HYAL1 are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency.

    Synonym: Hyaluronidase-1, Hyal-1, Hyaluronoglucosaminidase-1, Lung Carcinoma Protein 1, LuCa-1, HYAL1, LUCA1

    Poids moléculaire
    47.2 kDa
    UniProt
    Q12794
    Pathways
    Glycosaminoglycan Metabolic Process
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