IP6K1 Protein (His-GST)
Aperçu rapide pour IP6K1 Protein (His-GST) (ABIN7196191)
Antigène
Voir toutes IP6K1 ProtéinesType de proteíne
Origine
Source
Pureté
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Purification/Conjugué
- Cette IP6K1 protéine est marqué à la His-GST.
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Fonction
- Recombinant Human IHPK1 Protein (His & GST Tag)
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Séquence
- Met 1-Gln 441
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Attributs du produit
- A DNA sequence encoding the human IHPK1 (Q92551-1) (Met1-Gln441) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
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Stérilité
- 0.2 μm filtered
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niveau d'endotoxine
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Inositol Hexakisphosphate Kinase 1 (IP6K1) (AA 182-275) protein (GST tag)
IP6K1 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
Inositol Hexakisphosphate Kinase 1 (IP6K1) (AA 1-441) protein (His tag)IP6K1 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Supplied as sterile solution of 20 mM Tris, 500 mM NaCl, pH 8.0, 10 % glycerol
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Stock
- -20 °C
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Stockage commentaire
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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Date de péremption
- 6 months
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- IP6K1 (Inositol Hexakisphosphate Kinase 1 (IP6K1))
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Autre désignation
- IHPK1
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Sujet
- IHPK1,PiUS,IHPK1 is a inositol hexaphosphate kinase (IHPK) protein which belongs to the inositol phosphokinase (IPK) family. IHPK proteins are likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). IHPK1 may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4 and affect the growth suppressive and apoptotic activities of interferon-beta in some ovarian cancers. During cell death, IHPK1 activity is enhanced, and intracellular InsP7 level is augmented. The distribution of IHPK1 or another predisposing gene affected by position effect of translocation may explain the T2DM phenotype at least in this family.
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Poids moléculaire
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Calculated MW: 78.0 kDa
Observed MW: 88 kDa
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ID gène
- 9807
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UniProt
- Q92551
Antigène
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