IL-22 Protein (mFc Tag)

N° du produit ABIN7320587

Protéine Recombinant IL-22 exprimée dans Human Cells.

Aperçu rapide pour IL-22 Protein (mFc Tag) (ABIN7320587)

Antigène: IL-22 (IL22) (Interleukin 22 (IL22))

Type de proteíne: Recombinant

Origine: Souris

Source: Human Cells

Pureté: > 95 % as determined by SDS-PAGE

Détail du produit

Purification/Conjugué: Cette IL-22 protéine est marqué à la mFc Tag.

Fonction: Recombinant Mouse Interleukin-22/IL-22 Protein (mFc Tag)

Séquence: Leu34-Val179

Attributs du produit: Recombinant Mouse Interleukin-22 is produced by our Mammalian expression system and the target gene encoding Leu34-Val179 is expressed with a mFc tag at the C-terminus.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: IL-22 (IL22) (Interleukin 22 (IL22))

Autre désignation: Interleukin-22/IL-22

Sujet:

Background: Interleukin-22 (IL-22) was initially identified as a gene induced by IL-9 in mouse T cells and mast cells. Mouse IL-22 cDNA encodes a 179 amino acid residue protein with a putative 33 amino acid signal peptide that is cleaved to generate a 147 amino acid mature protein that shares approximately 79 % and 22 % sequence identity with human IL22 and IL10, respectively. IL22 has been shown to activate STAT-1 and STAT-3 in several hepatoma cell lines and up-regulate the production of acute phase proteins. IL-22 is produced by normal mouse T cells upon Con A activation. Mouse IL-22 expression is also induced in various organs upon lipopolysaccharide injection, suggesting that IL-22 may be involved in inflammatory responses. The functional IL-22 receptor complex consists of two receptor subunits, IL-22R (previously an orphan receptor named CRF2-9) and IL-10Rβ (previously known as CRF2-4), belonging to the class II cytokine receptor family.

Synonym: Interleukin-22, IL-22, IL-TIF alpha, IL-10-related T-cell-derived-inducible factor, IL-TIF, IL22, Interleukin-22a, IL-22a

Poids moléculaire: 43.8 kDa

UniProt: Q9JJY9