Lactoferrin Protein (His tag)

N° du produit ABIN7320159

Protéine Recombinant Lactoferrin exprimée dans HEK-293 Cells.

Aperçu rapide pour Lactoferrin Protein (His tag) (ABIN7320159)

Antigène: Lactoferrin (LTF) (Lactotransferrin (LTF))

Type de proteíne: Recombinant

Origine: Souris

Source: HEK-293 Cells

Pureté: > 92 % as determined by SDS-PAGE

Détail du produit

Purification/Conjugué: Cette Lactoferrin protéine est marqué à la His tag.

Fonction: Recombinant Mouse Lactotransferrin/LTF Protein (His Tag)

Séquence: Met 1-Gln 707

Attributs du produit: A DNA sequence encoding the mouse LTF (AAH06904.1) (Met 1-Gln 707) was expressed, with a C-terminal polyhistidine tag.

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: Lactoferrin (LTF) (Lactotransferrin (LTF))

Autre désignation: Lactotransferrin/LTF

Sujet:

Background: Lactotransferrin, also known as Lactoferrin, Talalactoferrin and LTF, is a secreted protein which belongs to the transferrin family. Transferrins are iron binding transport proteins which can bind two Fe3+ ions in association with the binding of an anion, usually bicarbonate. Lactotransferrin has antimicrobial activity which depends on the extracellular cation concentration. Lactoferroxins A, B and C have opioid antagonist activity. Lactoferroxin A shows preference for mu-receptors, while lactoferroxin B and lactoferroxin C have somewhat higher degrees of preference for kappa-receptors than for mu-receptors. Lactoferrin / LTF is a globular glycoprotein that is widely represented in various secretory fluids, such as milk, saliva, tears, and nasal secretions. Lactoferrin / LTF is also present in secondary granules of PMN and is secreted by some acinar cells. Lactoferrin / LTF can be purified from milk or produced recombinantly. Human colostrum has the highest concentration, followed by human milk, then cow milk. Lactoferrin / LTF is one of the components of the immune system of the body, it has antimicrobial activity (bacteriocide, fungicide) and is part of the innate defense, mainly at mucoses. In particular, lactoferrin provides antibacterial activity to human infants. Lactoferrin interacts with DNA and RNA, polysaccharides and heparin, and shows some of its biological functions in complexes with these ligands.

Synonym: Csp82,Lf,MMS10R,Ms10r

Poids moléculaire: 77.2 kDa

Pathways: Transition Metal Ion Homeostasis