LAIR2 Protéine

N° du produit ABIN7196816

Détail du produit

Antigène: LAIR2 (Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Fonction: Recombinant Human LAIR2/CD306 Protein, Low Endotoxin

Séquence: Met 1-Pro 152

Attributs du produit: A DNA sequence encoding the human LAIR2 (NP_002279.2) (Met 1-Pro 152) was expressed and purified.

Pureté: > 94 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: 5 EU per 1 mg protein as determined by the LAL method. Frozen shipping is required

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: LAIR2 (Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2))

Autre désignation: LAIR2/CD306 (LAIR2 Produits)

Synonymes: CD306 Protein, leukocyte associated immunoglobulin like receptor 2 Protein, LAIR2 Protein

Sujet:

Background: Leukocyte-associated immunoglobulin-like receptor 2 ( LAIR2 ), also known as CD306, is a 131 amino acid protein containing one lg-like C2-type domain. It is expressed as a soluble receptor exhibiting high affinity for various collagen molecules to which it binds in a hydroxyproline-dependent manner. LAIR2 is a member of the immunoglobulin superfamily and was identified by its similarity to LAIR1, an inhibitory receptor present on mononuclear leukocytes. LAIR2 is thought to be secreted and may help modulate mucosal tolerance. As a natural competitor for LAIR1, soluble LAIR2 prevents binding of human LAIR1 to collagens and LAIR1 cross-linking, thereby regulating its inhibitory potential. Accordingly, LAIR2 is suggested to perform an immunoregulatory function.

Synonym: CD306,LAIR2,MGC71634,XXbac-BCX535A19.6

Poids moléculaire: 14.1 kDa

NCBI Accession: NP_002279