LUM Protein (AA 19-338) (His tag)

N° du produit ABIN7320810

Cette protéine Recombinant LUM est exprimée dans HEK-293 Cells.

Aperçu rapide pour LUM Protein (AA 19-338) (His tag) (ABIN7320810)

Antigène: LUM (Lumican (LUM))

Type de proteíne: Recombinant

Origine: Souris

Source: HEK-293 Cells

Pureté: > 95 % as determined by reducing SDS-PAGE.

Détail du produit

Attributs du protein: AA 19-338

Purification/Conjugué: Cette LUM protéine est marqué à la His tag.

Fonction: Recombinant Mouse Lumican/LUM Protein (His Tag)

Séquence: Gln19-Asn338

Attributs du produit: Recombinant Mouse Lumican is produced by our Mammalian expression system and the target gene encoding Gln19-Asn338 is expressed with a 6His tag at the C-terminus.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: LUM (Lumican (LUM))

Autre désignation: Lumican/LUM

Sujet: KSPG lumican,Keratan sulfate proteoglycan lumican,LDC,Lumican,Keratan sulfate proteoglycan lumican, mostly known as lumican, belongs to the SLRP class II subfamily and the small leucine-rich proteoglycan (SLRP) family. Lumican binds to laminin. It has positive regulation of transcription from RNA polymerase II promoter and transforming growth factor beta1 production. Lumican is expressed in a variety of tissues, including skin, artery, lung, cornea, kidney, bone, aorta, and articular cartilage. The abnormal connective tissue phenotype seen in the Lumican null mice shows the importance of the role of Lumican in collagen fibrillogenesis. In addition to the control of collagen fibril assembly, Lumican has been shown to play a role in the regulation of cell proliferation, migration, and adhesion.

Poids moléculaire:

Calculated MW: 37.4 kDa

Observed MW: 40-60 kDa

UniProt: P51885

Pathways: Glycosaminoglycan Metabolic Process