MYOZ2 Protein (His tag)

N° du produit ABIN7318797

Protéine Recombinant MYOZ2 exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour MYOZ2 Protein (His tag) (ABIN7318797)

Antigène: MYOZ2 (Myozenin 2 (MYOZ2))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Pureté: > 90 % as determined by reducing SDS-PAGE.

Détail du produit

Purification/Conjugué: Cette MYOZ2 protéine est marqué à la His tag.

Fonction: Recombinant Human Myozenin-2/MYOZ2 Protein (His Tag)

Séquence: Met 1-Leu264

Attributs du produit: Recombinant Human Myozenin-2 is produced by our E.coli expression system and the target gene encoding Met1-Leu264 is expressed with a 6His tag at the C-terminus.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from a 0.2 μm filtered solution of 10 mM Tris-HCl, pH 8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: MYOZ2 (Myozenin 2 (MYOZ2))

Autre désignation: Myozenin-2/MYOZ2

Sujet: C4orf5,Calsarcin-1,FATZ-Related Protein 2,MYOZ2,Myozenin-2,Myozenin 2 (MYOZ2) is a 264 amino acid protein that belongs to the myozenin family. MYOZ2 binds to Calcineurin, a phosphatase that is involved in calcium-dependent signal transduction in diverse cell types. MYOZ2 is one of the sarcomeric proteins and plays an important role in myofibrillogenesis and the modulation of calcineurin signaling. It may serve as intracellular binding proteins involved in linking Z line proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and plays an important role in the modulation of calcineurin signaling. Defects in MYOZ2 are the cause of familial hypertrophic cardiomyopathy type 16 (CMH16), a hereditary heart disorder.

Poids moléculaire:

Calculated MW: 30.9 kDa

Observed MW: 38 kDa

ID gène: 51778

UniProt: Q9NPC6