NCF2 Protein (His-GST)

N° du produit ABIN7317175

Protéine Recombinant NCF2 exprimée dans Baculovirus infected Insect Cells.

Aperçu rapide pour NCF2 Protein (His-GST) (ABIN7317175)

Antigène: NCF2 (Neutrophil Cytosolic Factor 2 (NCF2))

Type de proteíne: Recombinant

Origine: Humain

Source: Baculovirus infected Insect Cells

Pureté: > 90 % as determined by reducing SDS-PAGE.

Détail du produit

Purification/Conjugué: Cette NCF2 protéine est marqué à la His-GST.

Fonction: Recombinant Human NCF2/P67phox Protein (His & GST Tag)

Séquence: Met 1-Val526

Attributs du produit: A DNA sequence encoding the human NCF2 (AAH01606.1) (Met1-Val526) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile 20 mM Tris, 500 mM Nacl, 10 % glycerol, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: NCF2 (Neutrophil Cytosolic Factor 2 (NCF2))

Autre désignation: NCF2/P67phox

Sujet: NCF-2,NOXA2,P67-PHOX,P67PHOX,NCF2, also known as NCF-2 and p67phox, is a subunit of the multi-protein NADPH oxidase complex. NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in NCF2 gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms.

Poids moléculaire:

Calculated MW: 87.6 kDa

Observed MW: 80-90 kDa

ID gène: 4688

UniProt: P19878