NCF2 Protéine

N° du produit ABIN7317174

Cette protéine Recombinant NCF2 est produite dans Baculovirus infected Insect Cells.

Aperçu rapide pour NCF2 Protéine (ABIN7317174)

Antigène: NCF2 (Neutrophil Cytosolic Factor 2 (NCF2))

Type de proteíne: Recombinant

Origine: Humain

Source: Baculovirus infected Insect Cells

Pureté: > 85 % as determined by reducing SDS-PAGE.

Détail du produit

Fonction: Recombinant Human NCF2/P67phox Protein

Séquence: Met 1-Val526

Attributs du produit: A DNA sequence encoding the human NCF2 (AAH01606.1) (Met1-Val526) was expressed and purified with two additional amino acids (Gly & Pro) at the N-terminus.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 20 mM Tris, 300 mM NaCl, pH 8.0

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: NCF2 (Neutrophil Cytosolic Factor 2 (NCF2))

Autre désignation: NCF2/P67phox

Sujet:

Background: NCF2, also known as NCF-2 and p67phox, is a subunit of the multi-protein NADPH oxidase complex. NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in NCF2 gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms.

Synonym: NCF-2,NOXA2,P67-PHOX,P67PHOX

Poids moléculaire: 59.9 kDa